Preliminary Program
Programme-at-a-GlanceMonday, October 13th 2008
Back To Top| 16:00 - 18:00 | Opening Ceremony |
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| Auditorium 1 | Chairs: Lynn Morris, Glenda Gray, Koleka Mlisana, Carolyn Williamson |
| Sizophila Choir | |
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Welcome and Opening Remarks Lynn Morris |
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South Africa's Commitment to AIDS Vaccine Development Honourable Minister Ms Barbara Hogan |
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Scientific Innovation and the Path to an AIDS Vaccine Deputy Minister Mr Derek Hanekom |
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What Challenges/Opportunities Face African Scientists in the Development of an HIV Vaccine? Malegapuru Makgoba |
HIV Vaccine Research and the Global HIV Vaccine Enterprise Alan Bernstein |
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Sang-froid in a Time of Trouble Stanley A Plotkin |
| 18:00 | Welcome Reception |
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Tuesday, October 14th 2008
Back To Top| 08:30 - 10:00 | Plenary Session 01 |
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| Chairs: Nelson Michael and Alash’le Abimiku | |
| 08:30 - 09:00 | Vaccine-Induced Immunity in T-Cell Based Candidate HIV Vaccines M Juliana McElrath |
| 09:00 - 09:30 | Community Issues Relating to Prevention Research in Developing Countries Pedro Goicochea |
| 09:30 - 10:00 | Antibody Protection in the Macaque Model Dennis R Burton |
| 10:00 - 10:30 | Tea/Coffee Break |
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| 10:30 - 12:30 | Parallel Oral Abstract Session 01 |
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HIV Transmission and Acute HIV Infection Jesus F. Salazar-Gonzalez Debrah L. Boeras Gama P Bandawe Qinxue Hu Catherine M Card Michael K Liu Hanneke Schuitemaker Hendrik Streeck NIA Winner |
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10:30 - 12:30 |
Parallel Oral Abstract Session 02 |
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T Cell Vaccines and Animal Models Brad R Jones NIA Winner Fiona Tanzer David A Garber Tomas Hanke R Keith Reeves Christiane Stahl-Hennig Meritxell Genescà Ferrer Rajeev Gautam |
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10:30 - 12:30 |
Parallel Oral Abstract Session 03 |
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Neutralizing Antibodies and Immune Escape Lautaro Gabriel Perez Xiang-Peng Kong Dimiter S Dimitrov Penny L Moore NIA Winner Marta Massanella M Anthony Moody David Davis Shiu-Lok Hu |
| 12:30 - 14:30 | Lunch |
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| 13:00 - 13:30 | Keynote Lecture |
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| Chair: Anthony Mbewu | |
| HIV Vaccines: Science and Policy Anthony S Fauci |
| 13:30 - 14:30 |
Parallel Poster Discussion Group 01
Parallel Poster Discussion Group 02
Parallel Poster Discussion Group 03
Parallel Poster Discussion Group 04 |
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| 14:30 -15:30 | Parallel Special Session 01 Preparing for Future Efficacy Trials |
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| Moderators: Glenda Gray and Barney Graham | |
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HIV Vaccine Development in the Post STEP/Phambili Era Lawrence Corey |
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Learning from the Past: How Prepared are we for Future HIV Vaccine Efficacy Trials in Uganda? Pontiano Kaleebu |
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Reassessing the Screening Test of Concept (STOC) Trial Design for AIDS Vaccines Frances Priddy |
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Vaccine Efficacy Trial Design Considerations in a Post-STEP Era Steve Self |
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Regulatory Considerations for Future Efficacy Trials Helen Rees |
| 14:30 -15:30 |
Parallel Oral Abstract Session 04 |
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Immune Responses at Mucosal Sites Alfred Bere Mario Roederer Pamela A Kozlowski David JM Lewis |
| 14:30 -15:30 | Parallel Special Session 02 Innovations in AIDS Vaccine Discovery |
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| Moderator: Wayne Koff | |
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Reverse Immunization: A Novel Strategy for In Vivo HIV Neutralization K Reed Clark |
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Engineering a Human Immune System In Vitro for Rapid Vaccine Evaluation William L Warren |
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Immune Complexes as HIV-1 Vaccine Candidate Sanjay Phogat |
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Toward a Chimeric Live Attenuated Vaccine for Human Immunodeficiency Virus Clayton Beard |
| 15:30 - 16:00 | Tea/Coffee Break |
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| 16:00 - 18:00 | Parallel Debate 01 Should Animal Models be a Gatekeeper for Human Clinical Trials? |
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| Moderator: Margaret (Peggy) Johnston | |
| Yes Team: R Paul Johnson and Jeffrey D Lifson No Team: David Weiner and Jerald C Sadoff |
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| 16:00 - 16:15 | Yes Team Opening Statement |
| 16:15 - 16:30 | No Team Opening Statement |
| 16:30 - 17:00 | Rebuttals (Both Teams) |
| 17:00 - 17:50 | Audience Questions and Comments |
| 17:50 - 18:00 | Final Comments |
| 16:00 - 18:00 | Parallel Symposium 01: The Search for New and More Broadly Neutralizing Antibodies |
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| Moderators: John Mascola and James Robinson | |
| 16:00 - 16:20 | Profiling the Specificity of Neutralizing Activity in a Panel of HIV+ Plasmas from Subtypes B and C Chronic Infections James Binley |
| 16:20 - 16:40 | The Search for New Broadly Neutralizing Antibodies and Methods of their Induction: Finding a Path to Successful HIV-1 Vaccine Development Barton F Haynes |
| 16:40 - 17:00 | Frequency and Phenotype of HIV Envelope-specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies Mark Connors |
| 17:00 - 17:20 | Novel Neutralizing Monoclonal Antibodies to HIV-1 Derived from Humans and Llamas Robin Weiss |
| 17:20 - 17:40 | A Panel of HIV-1 Neutralizing Antibodies Isolated from Non-clade B HIV-1 Infected Donors Davide Corti |
| 17:40 - 18:00 | Search for Broadly Neutralizing Antibodies against HIV Using a Single Cell Approach Richard Wyatt |
| 18:00 | Gala Dinner at Moyo, Spier Wine Estate, Stellenbosch |
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Wednesday, October 15th 2008
Back To Top| 08:30 - 10:00 | Plenary Session 02 |
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| Chairs: Brigitte Autran and Seth Berkley | |
| 08:30 - 09:00 | Correlates of Protective Vaccine Induced T Cell Immunity Bruce D Walker |
| 09:00 - 09:30 | Emerging Ethical Issues in Preventative HIV Vaccinne Research Ruth Macklin |
| 09:30 - 10:00 | HIV Vaccine Efficacy Trials: Past, Present and Future Susan Buchbinder |
| 10:30 - 12:30 | Parallel Oral Abstract Session 05 |
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Updates on Clinical Trials George N Pavlakis Eva Van Braeckel Stephen C De Rosa Samuel O Pine Muhammad Bakari Mary Marovich Gavin J Churchyard Punnee Pitisuttithum |
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| 10:30 - 12:30 |
Parallel Oral Abstract Session 06 |
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Cellular Immunity and Escape Pholo W Maenetje Alexandre Harari Florencia Pereyra Guido Ferrari Margaret E Feeney Julia G Prado Jonathan Carlson Yaoyu E Wang |
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| 10:30 - 12:30 |
Parallel Oral Abstract Session 07 |
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Novel Enevelope Immunogens Donald Van Ryk D Cameron Dunlop Yu Geng Mark Melchers Michael Cho S Munir Alam Gilad Ofek T Matt Holl |
| 12:30 - 13:30 | Lunch |
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| 13:30 - 15:30 | Parallel Oral Abstract Session 08 |
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A Delicate Balancing Act: Vulnerability and Safeguards Simon Sigirenda Paula M Frew Janan Dietrich Heather B Jaspan Kayitesi Kayitenkore Peter A Newman Gabriela Calazans Kimberly K Louis |
| 13:30 - 15:30 | Parallel Debate 02 Should there be Further Large Scale Efficacy Testing of T-Cell Based Vaccines that do not Induce Broadly Neutralizing Antibodies? |
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| Moderator: John Moore | |
| 13:30 - 14:20 |
Should there be Further Efficacy Testing of T-Cell Based Vaccines that do not Induce Broadly Neutralizing Antibodies?
Antibodies and T Cells: Horses for Courses
We should still Test T Cell Based Vaccines
An Analysis of HIV Vaccine Efforts |
| 14:20 - 14:40 | Rebuttal Phase |
| 14:40 - 15:30 | Final Comments and Questions |
| 13:30 - 15:30 | Parallel Oral Abstract Session 09 |
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No Time for Recall: Innate Immune Responses Daniel E Zak NIA Winner Steven E Bosinger NIA Winner Erica Andersen-Nissen Galit Alter Amy Chung William H Carr Aida Sivro Jinghe Huang |
| 15:30 - 16:00 | Tea and Coffee Break |
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| 16:00 - 18:00 | Parallel Round Table 01 Converging of Prevention Technologies |
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| Moderators: Mitchell Warren and Helen Rees | |
| 16:00 - 16:20 | Can Vaccines And Microbicides be Co-developed? John Moore |
| 16:20 - 16:40 | Antiretroviral Prophylaxis: A Point of Convergence in the Scientific Agendas for Pre- and Post-exposure Prophylaxis, Microbicides and Perinatal HIV Prevention Salim Abdool Karim |
| 16:40 - 17:00 | Mechanism of HIV Entry into the Squamous Epithelium of the Female Genital Tract Tom J Hope |
| 17:00 - 17:20 | Vaccines and Microbicides? Getting the Best out of New Prevention Technology Robin Shattock |
| 17:20 - 17:40 | Prevention Research Efforts in Cape Town Linda-Gail Bekker |
| 17:40 - 18:00 | HIV Prevention: Designing and Re-Designing HIV Vaccine Clinical Trials Magdalena E Sobieszczyk |
| 16:00 - 18:00 | Parallel Symposium 02 Systems Biology to Unravel and Decipher the Interface between Innate and Adaptive Immunity |
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| Moderators: Alan Aderem and Clive Gray | |
| 16:00 - 16:20 | Population Diversity in HIV-Associated Genes: Consequences and Cautions Cheryl Winkler |
| 16:20 - 16:40 | Plasmacytoid Dendritic Cells in Lymphoid Organs: Comparative Studies at the Interface Between Innate and Adaptive Immunity Against HIV Anne Hosmalin |
| 16:40 - 17:00 | HIV and Synapses Olivier Schwartz |
| 17:00 - 17:20 | Genetically Determined Differences in NK Cell Function in HIV-1 Infection Marcus Altfeld |
| 17:20 - 17:40 | Systems Biology approaches Predict the Immunogenicity of the Yellow Fever Vaccine-17D in Humans Bali Pulendran |
| 17:40 - 18:00 | A Systems Approach to Dissecting Immunity Alan Aderem |
| 16:00 - 18:00 | Parallel Symposium 03 Biology of Vectors / Next Generation Vaccine Vectors |
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| Moderators: Dan H Barouch and Anna-Lise Williamson | |
| 16:00 - 16:20 | Induction of Potent T Cell Immunity in Macaques by EP DNA + Molecular Adjuvants David Weiner |
| 16:20 - 16:40 | Live Attenuated Measles Virus Vaccine Vector: Challenges and Prospectives Hussein Y Naim |
| 16:40 - 17:00 | Novel Adenovirus Vector-Based Vaccines for HIV-1 Dan H Barouch |
| 17:00 - 17:20 | Can Effector-Memory T Cell Responses Contribute to AIDS Vaccine Efficacy? Louis Picker |
| 17:20 - 17:40 | A Comparative Analysis of Toll-like Receptor Ligands as Vaccine Adjuvants with SIV Gag Protein in Non-human Primates Robert Seder |
| 17:40 - 18:00 | Novel HIV Vaccines for Southern Africa Anna-Lise Williamson |
| 18:00 - 20:00 | Poster Session |
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Thursday, 16 October 2008
Back To Top| 08:30 -10:00 | Plenary Session 03 |
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| Chairs: Jack Whitescarver and Nina Russell | |
| 08:30 - 09:00 | A New Look at the Transmitted Virus and its Source in the
Genital Tract Ronald Swanstrom |
| 09:00 - 09:30 | HIV Prevention: in Search of a Future James McIntyre |
| 09:30 - 10:00 | Mucosal Immunity in HIV and SIV Infection Guido Silvestri |
| 10:00 - 10:30 | Tea and Coffee Break |
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| 10:30 - 12:15 | Late Breaker Session |
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| Chairs: Joep Lange and Richard A Koup Holly Janes Glenda Gray Nicole Frahm Nancy Wilson Yiming Shao Gnana Gnanakaran Robert Pejchal Gary Nabel M Anthony Moody Caroline Tiemessen |
| 12:15 - 13:15 | Rapporteur Session |
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| Chairs: Lynn Morris and Yves Levy | |
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Vaccine Concepts and Design Edward Rybicki |
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T Cell Immunology and Innate Immunity Galit Alter | |
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B Cell Immunology, Neutralizing Antibodies and Mucosal Immunology Ralph Pantophlet |
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Clinical Trials Jintanat Ananworanich |
| 13:15 - 13:30 | Closing and Handover |
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| Chair: Lynn Morris | |
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AIDS Vaccine 2009 Yves Lévy |