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Capacity-Building Workshop: Statistical Methods in HIV Vaccine Trial Design

The Global HIV Vaccine Enterprise and the OCTAVE Project (Online Collaborative Training for AIDS Vaccine Evaluation), in close collaboration with the Brazilian Ministry of Health (Department of STD, AIDS and Viral Hepatitis and the Oswaldo Cruz Foundation - FIOCRUZ) and the University of São Paulo- USP, hosted a workshop on key statistical and epidemiologic methods applied to the design of early and late stage vaccine trial design.

As part of this workshop, participants reviewed fundamental statistical and clinical trial design concepts relevant to vaccine evaluation; discussed the activities of Data Safety and Monitoring Boards; reviewed findings from RV144 and explored the approach to define correlates of vaccine protection; and considered new ways to design studies that aim to evaluate combination HIV prevention strategies (e.g., vaccines and pre-exposure prophylaxis).

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Statistics Workshop Faculty and Participants

Materials

Sponsors

This workshop is supported by the NIH Office of AIDS Research, the Government of Canada, the Brazilian Ministry of Health (Department of STD, AIDS and Viral Hepatitis and the Oswaldo Cruz Foundation - FIOCRUZ) and the University of São Paulo - USP.  The Capacity-building series is a program of the Global HIV Vaccine Enterprise, a unique alliance of independent organizations around the world dedicated to accelerating the development of a preventive HIV vaccine.

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