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Long-Term Thermostabilization of Live Poxviral and Adenoviral Vaccine Vectors at Supraphysiological Temperatures in Carbohydrate Glass

A team of scientists at Oxford University and Nova Laboratories found a simple and inexpensive way of keeping vaccines stable even at tropical temperatures, researchers report in the journal Science Translational Medicine.  Researchers used a patented system from Nova called HydRIS that involves mixing the vaccine with the sugars trehalose and sucrose, and leaving it to dry out on a filter or membrane. The technology developed by the scientists could transform immunization campaigns in the developing world by removing the need for costly infrastructure, like refrigerators and freezers that require power and can break down, and highly trained staff.   The study abstract is available at: http://stm.sciencemag.org/content/2/19/19ra12.abstract.

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