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ID#:NL-ID-102    Posted: 3 Jan 2012
Scientist -- T cell Immunology
Type of Position: Full-time   
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Deadline: 1 Jan 2038
Crucell is a global biotech company that focuses on the development, pro­duction and marketing of vaccines, recombinant proteins and antibodies to prevent and combat infectious and other diseases. Within Crucell talented, entrepreneurial people are working in a dynamic cul­ture in which innovation and a 'can do' state of mind are the central points. In order to strengthen our team we are continuously looking for enthusiastic, talented people who have the ambition to develop themselves and can be of value to Crucell.
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The Bacterial Vaccine Research department is part of the Innovation and Discovery Laboratory and focuses on the research and development of vaccines against infectious diseases. Within the Bacterial Vaccine Research department, the preclinical bacteriology group evaluates the immunogenicity and efficacy of potential vaccine candidates against several bacterial diseases in animal models. Assays to examine humoral and cellular immune responses will be developed and used to generate appropriate scientific data to show proof of concept and thereby enabling vaccine candidates to progress towards clinical phase evaluation.

Job Description:
This newly started bacterial vaccine research group is looking for a motivated scientist, who loves challenges, to evaluate the immunogenicity and efficacy of potential vaccine candidates. The role requires knowledge of immunological techniques such as T cell ELISPOT, proliferation assays, cytokine measurements, intercellular cytokine staining, FACS analysis and cell culturing.

The scientist will be responsible for the development of assays to measure immune responses of various bacterial vaccine candidates. The focus will be on T cell responses (Th1, Th2, Treg), cytokine induction and proliferation assays, intercellular cytokine staining and FACS analysis. 

  • The scientist will work in close collaboration with researchers and support the project leaders in evaluating vaccine candidates. 
  • The scientist will manage and mentor technicians to ensure high quality results.

Minimum Qualifications:

  • Ph.D plus 2 years experience in immunology/vaccinology
  • Experience is immunological techniques preferably T cells assays
  • Experience with cell culture techniques


  • You will actively contribute to the discovery and development of bacterial vaccines therefore we are looking for a flexible, motivated team-player with problem solving capabilities. 
  • Planning, organization and communication are very important skills for this position.

As part of Crucell’s recruitment policy, a pre-employment screening will take place during the recruitment process.


To send an application, use the "Apply Here" button above or send your short letter of motivation and CV to:

Human Resources
P.O. Box 2048
2301 CA Leiden