In this week’s news: Nature Precedings stops accepting papers, early treatment delays disease progression, an encounter with multiple HIV strains improves Ab responses, controversial results on HDAC inhibitors, microneedle patch boosts cytokines

• Nature Precedings stops accepting papers – Nature Publishing Group will archive all currently hosted papers, but will stop accepting any new manuscripts
• Early, temporary HIV treatment can postpone long-term therapy – a new study published in PLoS Medicine shows the clear benefit of early treatment in delaying disease progression
• HIV 'superinfection' boosts immune response – a study published in PLoS Pathogens found that exposure to different strains of HIV improves the breadth and potency of neutralizing antibodies in the infected person
• A study questions the role of HDAC inhibitors in HIV cure research – in an update from the Keystone conference, Richard Jeffreys reports on a study that contradicts the promising results from several laboratories by showing no difference in HIV RNA levels in the blood after treatment with HDAC inhibitors
• Next generation: A painless vaccine patch – vaccine delivery mechanism with a patch full of microneedles leads to a local increase in cytokines and improves immune responses