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Posted: 11 May 2012
 

Latest research highlights: Cytoplasmic tail of gp41 has a complex role in determining Env conformation, repeated immunizations fail to elicit bNAbs (but many opportunities remain), adding GM-CSF to an SIV vaccine abolishes protection, T-cell mapping studies post RV144. Reviews: HIV latency, host restriction factors.

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Posted: 8 Feb 2012
 

In this week's Journal Club, Dr. Denise Hsu reviews two recent attempts to improve immune responses to DNA vaccines using plasmids that code for immune-modulatory cytokines.

 

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Posted: 13 Jan 2012
 

The past several years brought us a wealth of new broadly-neutralizing antibodies (bnAbs), many of which are orders of magnitude more potent and many times more broad than the classical bnAbs, such as b12 or 2G12. How can we use this wealth to prevent or treat HIV infections?

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Posted: 23 Dec 2011
 

In this week's Journal Club, Andrew Scheibe discusses the difficult road to ending the AIDS epidemic and considers the global economic challenges to UNAIDS’ proposed “Investment Framework.”


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Posted: 16 Dec 2011
 
Author: Hayley Crawford

In this week's Journal Club, Hayley Crawford ponders on the implications of correlates analysis of the RV144 trial results and goes over recent data on immunogenicity of several T-cell vaccines.

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